Analysis of immune response of stressed male mice during Chlamydia muridarum lung infection

Chlamydia lung infection caused by trachomatis is a serious particularly in infants but there are few studies about infection. Chlamydial genital and infections mice frequently done with muridarum. The purpose of our study was to explore the effect stress chlamydia male mice. We hypothesize that changes level cytokine production monocytes during As result from these include counting live cells, differentiation proliferation bone marrow derived where showed non-stressed dendritic cells (DCs) WT stressed macrophages (MO) had sufficient study. No difference IL-b non-stress observed. Beta2-adrenergic receptor (b2-AR agonist (fenoterol) antagonist (ICI 118 551) treatment resulted agonists antagonists. TNF-alpha high compared for MO. LPS stimulated DC no However, decreased. IFN-g, Con A- LPS-treated splenic T cells. In contrast IL-5, IL-10, IL-23 treated norepinephrine bet2-adrenergic agonist, Fenoterol. Overall, cytokines shows variation may have roles enhancing protection or increased